Some malware camouflage themselves as iexplore.exe, so you need to check the path it is loading from.
There are different files with the same name:
"$WindowsRegKey%update" definitely not required.
"Explorer Updater" definitely not required. Added by the SDBOT-WO WORM! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Iexplore" definitely not required. Added by the BOXER TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"IEXPLORE" definitely not required. Added by the APHEXDOOR TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Iexplore Services" definitely not required. Added by an unidentified VIRUS, WORM or TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Internet Explorer" definitely not required. Added by the RBOT-EY WORM! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Java Runtimes" definitely not required. Added by the KILLAV.B TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Microsoft IE" definitely not required. Added by the FORBOT-AG WORM! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Microsoft Internet Explorer" definitely not required. Downloader trojan. Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"OPTIMIZER" definitely not required. Added by the EVIVINC TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"Program in Windows" definitely not required. Added by a variant of the LOVGATE WORM! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"slide" definitely not required. Added by the GASLIDE TROJAN! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!
"System Configuration" definitely not required. Added by the RANDEX.AD WORM! Note - this is not the legitimate Internet Explorer (iexplore.exe) process, which should not appear in Msconfig/Startup unless you add it manually!