In the program file is not the virus main source to run the program it's in User or Application Data folder.
Use combofix from bleepingcomputer.com, then go download malwarebytes from softpedia.com or cnet.com and use it(rename the installer if it doesn't let you install it such as winlogon.exe), then clean the rest of the virus with superantispyware from softpedia.com or superantispyware.com.
Future Protection use this wizard to recommend security protection for your system:
http://www.techsupportalert.com/secwiz
Or Manually:
Terminating the process:
1.I verify that a Rogue is present. This isn't hard, since it's usually popping up just about every few seconds.
2.Click CTRL-ALT-DELETE (if it's available)
3.Click Task Manager
4.Click Processes
5.Find a process that usually contain all numbers. For example 2342342.exe. If you do not see all numbers then your rogue has a name like...SystemSecurityPro.exe or GreenAV.exe...etc.
6.Select that process and click end process.
7.At this point the rogue process has been terminated.
Removing Rogue Anti-virus that is named with random numbers.
1.Click Start
2.Click Run (or for Vista type in the start search box)
3.For windows xp type: C:\documents and settings\all users\Application Data and click OK. A window will open containing a folder with about 8 numbers. Your Rogue is in there. Delete that folder.
4.For Windows Vista type C:\users\all users in the "start search" box and click enter. Your randomly named folder with about 8 digits should be in there. Delete it.
Removing Rogue Anti-Virus that has a name like System Guard Pro, AV2010, etc
1.Open Windows Explorer.
2.Open your C:\ drive.
3.Open Program Files
4.Find the Rogue and Delete the folder.