Are you using a firewall: you absolutely must use one.
Do you have open ports; close them.
Do you have exceptions: only allow ones you are certain are OK.
The three products you mentioned protect against viruses not spyware. You must have full time (active) spyware protection and full time (active) virus protection.
I strongly recommend you go through the following procedure to clean your computer and greatly reduce the chances of reinfection with malware. All products are free.
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Update your antivirus and run a full scan.
If you do not have full time (active) virus protection install:
AVG Antivirus 7.5 Free Edition
http://free.grisoft.com/freeweb.php/doc/avg-anti-virus-free/lng/us/tpl/v5
http://www.download.com/AVG-Anti-Virus-Free-Edition/3000-2239_4-10669237.html?tag=lst-0-1
or
Free antivirus - avast! 4 Home Edition
http://www.avast.com/eng/avast_4_home.html
or
AOL Active Virus Shield
http://www.activevirusshield.com/antivirus/freeav/index.adp
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Install Windows Defender (full time spyware protection)
Perform a full scan.
http://www.microsoft.com/athome/security/spyware/software/default.mspx
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Install the following five programs and run weekly or at least monthly. You need all five. They are not a substitute for full time spyware and virus protection. They will greatly increase your protection no matter what active virus and spyware protection you are using.
Ad-Aware SE Personal (update + full scan)
http://www.lavasoftusa.com/products/ad-aware_se_personal.php
Spybot Search & Destroy (update + immunize + scan)
Do not enable Tea Timer and SDHelper
After installation: update + scan + immunize
http://www.safer-networking.org/en/mirrors/index.html
SpywareBlaster: Update then open and click “enable all protection”.
http://www.javacoolsoftware.com/spywareblaster.html
SUPERAntiSpyware free version: (update + scan)
http://www.superantispyware.com/
CCleaner: Do not install toolbar option
Removes tracking cookies, unneeded files, history
In options.
Set to run when computer starts.
Place cookies you want to keep in save list
http://www.ccleaner.com/
Note if a scan detects a problem but is unable to remove the problem, start the computer in safe mode with the internet line disconnected and run a full scan.
In severe cases your system restore files will also be infected. In these cases you will need to turn off system restore to prevent malware hiding in the system restore files and reinfecting the computer during removal or during a future system restore. Turning off system restore deletes the system restore files.
Right click on "my computer"> Properties > System Restore Tab > Check box turn of system restore
After the malware is removed turn on system restore.
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Run this time only
CWShredder: run
http://www.trendmicro.com/cwshredder/
Roguefix.bat
http://www.internetinspiration.co.uk/roguefix.htm#uninstall
Shoot The Messenger
http://www.grc.com/stm/shootthemessenger.htm
SmitFraudFix
http://www.geekstogo.com/forum/How_to_use_SmitFraudFix-t109268.html
Vundo Fix and VirtumundoBegone (if VundoFix does not work)
http://www.bleepingcomputer.com/forums/topic18610.html
VX2 tool for Ad-Aware and run tool (Install and run)
http://www.lavasoftusa.com/support/securitycenter/vx2_cleaner.php
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Additional run this time and monthly
Microsoft OneCare Live, run “full service scan”
Updates windows, virus and spyware scan, disk cleanup, disk fragmentation (if needed), backs up registry and then cleans registry, and checks for open firewall ports
http://onecare.live.com/site/en-us/default.htm
Malicious Software Removal Tool (run “full scan”)
http://www.microsoft.com/security/malwareremove/default.mspx
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Rootkit Removal Guide
http://safecomputing.umn.edu/guides/scan_unhackme.html
Rootkits Removers (Pick any 2 install and run a different one each month)
AVG Anti-Rootkit
http://www.grisoft.com/doc/products-avg-anti-rootkit-update-app-art/?ver=1.1.0.29
F-Secure BlackLight
http://www.f-secure.com/blacklight/
Sophos Anti-Rootkit
http://www.sophos.com/products/free-tools/sophos-anti-rootkit.html
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Online Free Scanners:
Run Trend Micro, Kaspersky, and Panda Scan now.
Run a different one each month.
Trend Micro: HouseCall Free Scan (removes what it finds)
http://housecall.trendmicro.com/
BitDefender Online Scanner http://www.bitdefender.com/scan8/ie.html
Kaspersky Labs Online Scanner http://www.kaspersky.com/virusscanner
McAfee http://us.mcafee.com/root/mfs/default.asp?affid=294
Panda ActiveScan Free Online Scanner http://www.pandasoftware.com/products/activescan?
Symantic Online Scanner http://security.symantec.com/sscv6/ssc_eula.asp?langid=ie&venid=sym&plfid=23&pkj=ALUFRHYTINMHDKDCWLL&vc_scanstate=2
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Additional Information read:
http://wiki.castlecops.com/Malware_Removal_and_Prevention:_Overview
http://wiki.castlecops.com/Malware_Prevention:_Prevent_Re-infection
http://www.castlecops.com/f67-Hijackthis_Spyware_Viruses_Worms_Trojans_Oh_My.html
http://aumha.org/a/quickfix.htm
http://aumha.org/secure.htm
http://aumha.org/a/parasite.php
http://www.castlecops.com/t102301-Hijackthis_Guidelines_Read_Before_Posting.html
http://www.techsupportforum.com/security-center/hijackthis-log-help/15968-please-read-before-posting-
http://forum.aumha.org/viewtopic.php?t=4075&sid=901703d08c2ace31389ffef2d84b6607